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MCU-i4 is protecting in opposition to ferroptosis-induced lack of neuronal network in human and murine neuronsExperimental: Dose expansion_sub-populace 2_higher dose of niraparib MTDs and/or applicant RP2Ds for elimusertib applied together with niraparib at the next fastened dose.Qualifying aberrations needs to be detected in both DNA or ribonuclei